PHARMACEUTICAL RESEARCH; RESEARCHERS AT YEREVAN STATE UNIVERSITY RELEASE NEW DATA ON PHARMACEUTICAL RESEARCH

Drug Law Weekly
July 22, 2008

According to recent research published in the International Journal
of Pharmaceutics, "The effect of dimethyl sulfoxide (DMSO) and its
nearest homologue diethyl sulfoxide (DESO) as a polar cosolvents on
the binding of vitamin E to water+ DMSO (DESO) containing reversed
micelles of sodium bis(2-ethylhexyl) sulf6succinate (AOT) has been
investigated by a spectrophotometric method."

"The results suggest that compare with water without organic
cosolvent-containing reversed micelles in this case an increase of
binding constant of vitamin E in reversed micelles takes place,"
wrote S.A. Markarian and colleagues, Yerevan State University (see
also Pharmaceutical Research).

The researchers concluded: "The results obtained shown that with
the addition of DMSO and DESO it will be possible to monitoring a
penetration of vitamin E into micellar core."

Markarian and colleagues published their study in International
Journal of Pharmaceutics (The spectrophotometric study of the binding
of vitamin E to water plus dimethyl sulfoxide and water plus diethyl
sulfoxide containing reversed micelles. International Journal of
Pharmaceutics, 2008;353(1-2):52-55).