GENERAL CHEMISTRY: RESEARCH RESULTS FROM R.D. KHACHIKYAN AND CO-AUTHORS UPDATE KNOWLEDGE OF GENERAL CHEMISTRY

Science Letter
October 14, 2008

"The example of vinylpyridinium salts to establish for the first
time the possibility of nucleophilic addition to the vinyl group in
quaternary ammonium salts, which provides evidence against the concept
that such reactions involve d orbitals. The nucleophilic addition
reaction was accomplished with triphenylphosphine and pyridine,"
researchers in Yerevan, Armenia report (see also General Chemistry).

"In the latter case, the suggested reaction scheme was confirmed by
the observation of the Wittig reaction under the action of carbon
dioxide and the Stevens reaggangement involving the double bond of the
pyridinium ring and migrating 2-phosphonioethyl group. Procedures for
preparing the starting vinylpyridinium salts," wrote R.D. Khachikyan
and colleagues.

The researchers concluded: "Reaction schemes were siggested."

Khachikyan and colleagues published their study in Russian Journal of
General Chemistry (Features of the reaction of 2,3-dihalopropanoic
acids with pyridines and nucleophilic addition to N-vinylpyridinium
salts. Russian Journal of General Chemistry, 2008;78(7):1452-1457).

For additional information, contact R.D. Khachikyan, National Academy
Science Armenia, Institute Organ Chemical, Ul Zakhariya Kanakertsi
167-A, Yerevan 375091, Armenia.