STUDY DATA FROM YEREVAN STATE UNIVERSITY UPDATE KNOWLEDGE OF SOLUTION CHEMISTRY

Science Letter
February 16, 2010

According to recent research from Yerevan, Armenia, "Aqueous
solutions of DNA in the presence of dipropylsulfoxide (DPSO) and of
dibutylsulfoxide (DBSO) have been studied using UV-vis spectroscopy
and density measurements."

"It has been shown that significant thermal denaturation of DNA
occurs when DPSO or DBSO are present. The results obtained were
compared with those obtained previously with dimethylsulfoxide (DMSO)
and diethylsulfoxide (DESO)," wrote M.G. Aznauryan and colleagues,
Yerevan State University (see also Solution Chemistry).

The researchers concluded: "It is suggested that the lowering of
the transition enthalpy with increasing length of the carbon chain
of the dialkylsulfoxides is due to significance contribution from
hydrophobic interactions."

Aznauryan and colleagues published their study in the Journal of
Solution Chemistry (Properties of DNA plus Dipropylsulfoxide or
Dibutylsulfoxide plus Water Ternary Solutions. Journal of Solution
Chemistry, 2010;39(1):43-50).

For additional information, contact S.A. Markarian, Yerevan State
University, Dept. of Chem, A Manukyan 1, Yerevan 0025, Armenia.

Publisher contact information for the Journal of Solution Chemistry is:
Springer, Plenum Publishers, 233 Spring St., New York, NY 10013, USA.